3199-05-1Relevant academic research and scientific papers
Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks
Dos Santos, Maurício Silva,Ferreira, Byanca Silva,Silva, Rafaela Corrêa,Souto, Bernardo Araújo
, p. 335 - 343 (2021/09/07)
Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.
A novel synthetic approach towards pyrazole-4-carboxamides using N-(3-(dimethylamino)-2-formylacryloyl)formamide
Jachak, Madhukar N.,Ghagare, Maruti G.,Birari, Dilip R.,Rote, Ramhari V.,Kazi, Muddassar A.,Jachak, Sanjay M.,Toche, Raghunath B.
experimental part, p. 569 - 576 (2011/07/30)
A novel synthesis of pyrazole-4-carboxamides is reported. The reaction of N-(3-(dimethylamino)-2-formylacryloyl)formamide, an intermediate obtained by Vilsmeier-Haack formylation of acetonitrile, with hydrazine hydrate or monosubstituted hydrazines provid
