320-36-5 Usage
Uses
Used in Pharmaceutical Industry:
4-NITRO-3-(TRIFLUOROMETHYL)BENZONITRILE& is used as a key intermediate in the synthesis of anti-inflammatory drugs, leveraging its electron-withdrawing properties to contribute to the drug's therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 4-NITRO-3-(TRIFLUOROMETHYL)BENZONITRILE& is utilized as a building block for the development of pesticides and herbicides, where its unique properties help in the creation of effective and targeted agrochemicals.
Used in Organic Synthesis:
4-NITRO-3-(TRIFLUOROMETHYL)BENZONITRILE& is employed as a valuable building block in organic synthesis, particularly for the preparation of heterocyclic compounds and biologically active molecules, due to its strong electron-withdrawing nature and the influence of the trifluoromethyl group.
Check Digit Verification of cas no
The CAS Registry Mumber 320-36-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 320-36:
(5*3)+(4*2)+(3*0)+(2*3)+(1*6)=35
35 % 10 = 5
So 320-36-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F3N2O2/c9-8(10,11)6-3-5(4-12)1-2-7(6)13(14)15/h1-3H
320-36-5Relevant academic research and scientific papers
A Homogeneous Method for the Conveniently Scalable Palladium- and Nickel-Catalyzed Cyanation of Aryl Halides
Burg, Finn,Egger, Julian,Deutsch, Johannes,Guimond, Nicolas
, p. 1540 - 1545 (2016/08/30)
Homogeneous conditions for the palladium-catalyzed cyanation of aryl halides were developed. This new system features a broad scope of aryl chlorides and bromides, uses 2-propanol or 1-butanol as solvent, and is readily scalable. The same conditions can also provide simple benzonitriles using the recently developed (TMEDA)NiCl(o-tolyl) precatalyst in conjunction with 1,1′-bis(diphenylphosphino)ferrocene (dppf) as a ligand.
Physical gelation of polar aprotic solvents induced by hydrogen bonding modulation of polymeric molecules
Ka, Duyoun,Seo, Myungeun,Choi, Hyungsam,Kim, Eun Hee,Kim, Sang Youl
supporting information; scheme or table, p. 5722 - 5724 (2010/09/18)
Poly(aryl ether amide) containing o-nitroanilide forms a physical gel in polar aprotic solvents by solvent-induced change of hydrogen bonding modes, in which hydrogen bonding acceptor solvent molecules break intramolecular hydrogen bonding of o-nitroanili
