32016-04-9Relevant academic research and scientific papers
Novel, selective mechanism-based inhibitors of the herpes proteases
Pinto, Ivan L.,West, Andrew,Debouck, Christine M.,DiLella, Anthony G.,Gorniak, Joselina G.,O'Donnell, Kevin C.,O'Shannessy, Daniel J.,Patel, Arunbai,Jarvest, Richard L.
, p. 2467 - 2472 (1996)
A novel class of inhibitor of the herpes proteases acting upon the catalytic apparatus by forming covalent complexes are described. Two new families of inhibitor, the spirocyclopropyl oxazolones and the benzylidine N-sulphonyloxyimidazolones, have been sh
Studies on 2-Methyl- and 2-Phenyl-4-arylmethylene-2-imidazolin-5-ones and Related Compounds
Badr, Mahmoud Zarif,El-Sherief, Hassan Ahmed Hassan,Tadros, Magda Ebeid
, p. 2267 - 2270 (2007/10/02)
Compounds 4-arylmethylene-2-methyl-2-oxazolin-5-ones and 4-arylmethylene-2-styryl-2-oxazolin-5-ones react with primary aromatic amines in the presence of anhydrous zinc chloride to give the corresponding 4-arylmethylene-2-methyl-2-imidazolin-5-ones and 4-
