32022-41-6 Usage
Derivative of 3,4-dichlorophenoxyacetic acid
2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE is a hydrazide derivative of this acidic compound, meaning it has a similar structure with a hydrazide functional group attached.
Common use as a herbicide
2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE is widely used in agriculture to control the growth of unwanted vegetation, making it an effective tool for weed management.
Growth regulation in plants
2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE acts as a growth regulator by interfering with the synthesis of indole-3-acetic acid, a crucial hormone for plant growth and development.
Disruption of cell division and growth
The herbicidal action of 2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE is due to its ability to disrupt the normal processes of cell division and growth in plants, ultimately leading to their inability to survive or reproduce.
Selective action on broadleaf plants
2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE is particularly effective against broadleaf plants, making it an important tool for weed control in crops without harming the crops themselves.
Importance in agriculture
Due to its selective action and herbicidal properties, 2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE plays a significant role in modern agriculture for effective weed management and crop protection.
Caution and safety regulations
As a potent herbicide, it is crucial to handle 2-(3,4-DICHLOROPHENOXY)ACETOHYDRAZIDE with care and follow safety regulations to minimize potential risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 32022-41-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,0,2 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32022-41:
(7*3)+(6*2)+(5*0)+(4*2)+(3*2)+(2*4)+(1*1)=56
56 % 10 = 6
So 32022-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H8Cl2N2O2/c9-6-2-1-5(3-7(6)10)14-4-8(13)12-11/h1-3H,4,11H2,(H,12,13)
32022-41-6Relevant academic research and scientific papers
NURR1 RECEPTOR MODULATORS
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Paragraph 0646; 2020; 2024-2027, (2020/09/08)
Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.
Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group
Maingot, Lucie,Elbakali, Jamal,Dumont, Julie,Bosc, Damien,Cousaert, Nicolas,Urban, Agathe,Deglane, Gaelle,Villoutreix, Bruno,Nagase, Hideaki,Sperandio, Olivier,Leroux, Florence,Deprez, Benoit,Deprez-Poulain, Rebecca
, p. 244 - 261 (2013/10/01)
Osteoarthritis is a disabling disease characterized by the articular cartilage breakdown. Aggrecanases are potential therapeutic targets for the treatment of this pathology. At the starting point of this project, an acylthiosemicarbazide was discovered to inhibit aggrecanase-2. The acylthiosemicarbazide Zn binding group is also a convenient linker for library synthesis. A focused library of 920 analogs was thus prepared and screened to establish structure-activity relationships. The modification of the acylthiosemicarbazide was also explored. This strategy combining library design and discrete compounds synthesis yielded inhibitor 35, that is highly selective for aggrecanases over a panel of metalloproteases and inhibits the degradation of native fully glycosylated aggrecan. A docking study generated binding conformations explaining the structure-activity relationships.
