32042-39-0Relevant academic research and scientific papers
Method for preparing formate-type compound
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Paragraph 0039; 0047; 0048, (2018/07/30)
The invention discloses a method for preparing a formate-type compound. The method comprises the following steps of: adopting an alcohol-type compound and 1,3-dihydroxyacetone as reaction raw materials, and under the existence of a composite catalyst and an oxidant, reacting for 2-48 hours in a reaction medium in a reactor at a reaction temperature of 25-100 DEG C so as to obtain the formate-typecompound. The method disclosed by the invention is simple, and is mild in reaction condition, and by the method, a target product can be obtained by low cost and high yield; the used catalyst has highcatalytic activity, and is easily separated from a reaction system to be repeatedly used; the whole process is environment-friendly, and the reaction raw material (1,3-dihydroxyacetone) is easily converted from a side product (glycerol) of biodiesel, so that the utilization of the glycerol is promoted.
METHOD OF CONTROLLING PESTS
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Page/Page column 2, (2008/06/13)
The present invention relates to pest control compositions and a method of employing as essential active ingredients formic acid derivatives. Several compositions based on various formic acid derivatives were prepared for pest control .
WATER SOLUBLE ESTERS OF [N-(4-AMINO-2-BUTYNYL)] WITH ANTICANCER ACTIVITY
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Page/Page column 46, (2008/06/13)
The present invention relates to water soluble esters of [N-(4-amino-2-butynyl)] or 4-(N-substituted amino)-2-butynyl-1-esters and methods for production of said esters and the use of the esters for treatment of cancer.
General base catalysis of ester hydrolysis
Stefanidis, Dimitrios,Jencks, William P.
, p. 6045 - 6050 (2007/10/02)
The hydrolysis of alkyl formates with leaving groups in the range pKa = 12-16 is catalyzed by substituted acetate anions. There is an increase in the Br?nsted β value for general base catalysis with decreasing pKa of the leaving alcohol and a complementary increase in -β1g with decreasing pKa of the catalyzing base, both of which are consistent with a value of pxy = ?β/-pK1g = ?β1g/-?pKBH ? 0.11. This result supports a class n mechanism of general base catalysis, in which a proton is abstracted from the nucleophilic water molecule by the base catalyst in the transition state; it is not consistent with the kinetically equivalent class e mechanism of electrophilic catalysis by general acids of a reaction with hydroxide ion, by proton donation to the leaving alcohol. Solvent deuterium isotope effects in the range kH2O/kD2O = 3.6-5.3 for the buffer-independent reaction and 2.5-2.8 for catalysis by CHaCOO- support concerted proton transfer and O-C bond formation. The secondary isotope effect for catalysis of the hydrolysis of LCOOMe by acetate ion is kD/kH = 1.05. Both nucleophilic and general base mechanisms of catalysis by acetate anions are observed for the hydrolysis of substituted phenyl formates with leaving groups of pKa = 7.1-10.1. A small value of β = 0.12 for general base catalysis of the hydrolysis of phenyl formate and p-methylphenyl formate represents catalysis of the addition of water by hydrogen bonding of water to the base catalyst. On the other hand, a larger value of β = 0.35 and a decrease in kH2O/kD2O to 1.2 were observed for general base catalysis of the hydrolysis of p-nitrophenyl formate. It is suggested that the increase in β with decreasing pK1g (an apparent "anti-Hammond effect") may be accounted for by a change in mechanism, from catalysis of a stepwise reaction of phenyl and p-methylphenyl formates to concerted general base catalysis of formyl transfer to water for the reaction of p-nitrophenyl formate.
Enol Formates: Ruthenium Catalysed Formation and Formylating Reagents
Neveux, Muriel,Bruneau, Christian,Dixneuf, Pierre H.
, p. 1197 - 1199 (2007/10/02)
The one-step synthesis of the enol formates, isopropenyl, hex-1-en-2-yl, and α-methylenebenzyl formates, directly from terminal alkynes and formic acid with arene-ruthenium(II) catalysts is reported.They have been shown to be effective formylating reagents, under mild and neutral conditions, to produce formamides from primary and secondary amines, formylamino esters, and in the presence of a catalytic amount of imidazole, formates from alcohols or phenols.
The preparation of esters of formic acid using boron oxide
Carlson, Charles G.,Hall, Judith E.,Huang, Yan Y.,Kotila, Sirpa,Rauk, Arvi,Tavares, Donald F.
, p. 2461 - 2463 (2007/10/02)
Boron oxide has been found to act as an efficient reagent in the preparation of a number of formate esters by the direct esterification of formic acid with the alcohol.The reaction is most appropriate for primary and secondery alcohols, including unsaturated alcohols.The formate ester so produced is free of contamination by unreacted alcohol.
