32047-74-8 Usage
Class
Heterocyclic compounds
Subclass
Diazepine derivatives
Natural occurrence
Not commonly found in nature
Synthesis
Primarily synthesized for research and pharmaceutical development
Potential applications
Development of new drugs for neurological and psychiatric disorders, study of structure-activity relationships of diazepine derivatives
Use in organic chemistry
Building block for synthesis of related compounds
Handling and storage
Requires careful handling and storage to prevent degradation and ensure stability for various applications
Check Digit Verification of cas no
The CAS Registry Mumber 32047-74-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,0,4 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 32047-74:
(7*3)+(6*2)+(5*0)+(4*4)+(3*7)+(2*7)+(1*4)=88
88 % 10 = 8
So 32047-74-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2/c1-16-11-12-7-3-4-8-13(12)17(2)15-10-6-5-9-14(15)16/h3-10H,11H2,1-2H3
32047-74-8Relevant academic research and scientific papers
Mechanistic insights into the palladium-catalyzed domino synthesis of 10,11-dihydro-5H-dibenzo[b,e][1,4]diazepines
Laha, Joydev K.,Satyanarayana Tummalapalli,Gupta, Ankur
, p. 4773 - 4779 (2014/08/05)
A palladium-catalyzed domino approach to the synthesis of 10,11-dihydro-5H-dibenzo[b,e][1,4]diazepines starting from o-phenylenediamines and 2-bromobenzyl bromides or tosylates has been developed. Mechanistic studies support the following domino sequence. Intermolecular mono-N-benzylation of the o-phenylenediamine through oxidative palladium insertion, primarily at the benzylic position of the 2-bromobenzyl bromide, is followed by intramolecular N′-arylation. The intramolecular N′-arylation is demonstrated to be facilitated by coordination of a remote auxiliary nitrogen atom to the palladium atom.
