320575-07-3

Upstream product

• 91751-24-5 (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal 
• 95514-04-8 (S)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 718629-10-8 (2S,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2-methoxymethoxy-3-methyl-butyric acid methyl ester 
• 320575-04-0 (2S,3R)-4-(tert-butyldiphenylsiloxy)-2-(methoxymethoxy)-3-methyl-1-butanol 
• 623938-88-5 (2R,3S,4S,6S)-4-benzyloxy-7-(tert-butyldiphenylsiloxy)-2,6-dimethyl-5-methoxymethoxyheptanal 
• 320575-05-1 (2S,3R)-4-(tert-butyldiphenylsiloxy)-2-(methoxymethoxy)-3-methyl-1-butanal 

Relevant academic research and scientific papers

Towards the total synthesis of tonantzitlolone - Preparation of key fragments and the complete carbon backbone

The first synthetic advances towards the novel diterpenoid tonantzitlolone 1 are described. The key steps in the synthesis involve a chromium(II) Reformatsky reaction, a diastereoselective C1 extension and an expeditious aldol coupling step of

A New Polymer-attached Reagent for the Oxidation of Primary and Secondary Alcohols

formula presented A new, polymer-bound reagent system for the efficient oxidation of primary alcohols to aldehydes and secondary alcohols to ketones in the presence of a catalytic amount of 2,2,6,6-tetramethyl-1-piperidinyloxyl (TEMPO) is described. In most cases, workup of this heavy metal-free oxidation is achieved by simple filtration followed by removal of the solvent. In selected examples this reagent was compared with the known polymer-bound permanganate and chromium(VI) reagents.