320576-39-4

Upstream product

• 161275-25-8 3-(3,4,6-tri-O-benzyl-β-D-glucopyranosyl)-1-propene 
• 74372-90-0 3,4,6-tri-O-benzyl-D-glucal epoxide 
• 320576-31-6 2,6-anhydro-1,3,4-tri-O-benzyl-5-O-[tert-butyl(dimethyl)silyl]-7,8-dideoxy-D-glycerol-L-gulo-nonitol 
• 320576-33-8 [[(5S,7S,8S,9S,10R)-8,9-bis(benzyloxy)-7-[(benzyloxy)methyl]-1,6-dioxaspiro[4,5]dec-10-yl]oxy](tert-butyl)dimethylsilane 
• 157794-06-4 2,6-anhydro-1,3,4-tri-O-benzyl-5-O-[tert-butyl(dimethyl)silyl]-7,8,9-trideoxy-D-glycerol-L-gulo-non-8-enitol 
• 157903-84-9 3-(3,4,6-tri-O-benzyl-α-D-glucopyranosyl)-1-propene 
• 55628-54-1 3,4,6-tri-O-benzyl-D-glucal 
• 1011723-04-8 glucal epoxide 
• 320576-37-2 (5R,7S,8S,9S,10R)-8,9-bis(benzyloxy)-7-[(benzyloxy)methyl]-1,6-dioxaspiro[4,5]decan-10-yl methanesulfonate 

Downstream Products

• 945930-06-3 (2S,4S,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-propyl-dihydro-pyran-3-one 
• 909533-39-7 (2S,3R,4R,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-propyl-tetrahydro-pyran-3-ol 

Relevant academic research and scientific papers

Cytotoxic effects of C-glycosides in HOS and HeLa cell lines

Fifty-two C-glycosides were synthesized and their in-vitro antiproliferative activity screened against human cervical carcinoma (HeLa) and osteosarcoma (HOS) cell lines. Nine of them had growth inhibitions (GI50 values) below 10 μM, the C-gluco

New insights into the conformational properties of α-C-glucosides

A series of alkyl α-d-C-glucopyranosides were synthesized and their conformational properties analyzed by CD and NMR spectroscopy. The conformational analysis revealed that the hydroxymethyl group populations (torsion angle ω, O1-C1-C2-O2) and those aroun

Diisobutylaluminium hydride (DIBAL-H) as a molecular scalpel: A new mechanistic proposal for a spiroketal rearrangement

Taking advantage of our knowledge of the capacity of DIBAL-H to de-O-alkylate, we propose an alternative mechanism for a spiroketal rearrangement described by E. Suàrez. We also show that this proposal can account for the formation of the secondary product, whose original structure we propose to correct.