945930-06-3Relevant academic research and scientific papers
Cytotoxic effects of C-glycosides in HOS and HeLa cell lines
Sanhueza, Carlos A.,Mayato, Carlos,Machin, Ruben P.,Padron, Jose M.,Dorta, Rosa L.,Vazquez, Jesus T.
, p. 3676 - 3681 (2008/02/05)
Fifty-two C-glycosides were synthesized and their in-vitro antiproliferative activity screened against human cervical carcinoma (HeLa) and osteosarcoma (HOS) cell lines. Nine of them had growth inhibitions (GI50 values) below 10 μM, the C-gluco
Antiproliferation and apoptosis induced by C-glycosides in human leukemia cancer cells
Sanhueza, Carlos A.,Mayato, Carlos,Garcia-Chicano, Maria,Diaz-Penate, Raquel,Dorta, Rosa L.,Vazquez, Jesus T.
, p. 4223 - 4227 (2007/10/03)
A large series of alkyl C-glycosides was synthesized from d-glucal or d-galactal. These compounds were screened against the human promyelocytic leukemia cell line (HL60), showing significant activity and apoptosis. Up to 13 C-glucopyranosides, but no C-ga
