3206-45-9Relevant academic research and scientific papers
METHOD FOR PRODUCING ALKENE STEREOSELECTIVELY
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Paragraph 0050; 0051, (2017/08/03)
PROBLEM TO BE SOLVED: To provide a method for producing alkene efficiently and stereoselectively, and tetrazole that is a reaction intermediate useful for the production method and represented by formula (2). SOLUTION: The present invention provides a met
Alkylation of thiols with trichloroacetimidates under neutral conditions
Duffy, Brian C.,Howard, Kyle T.,Chisholm, John D.
supporting information, p. 3301 - 3305 (2015/03/04)
Trichloroacetimidates are displaced with thiols to form the corresponding sulfides without the need for an added acid or base by simply heating the reactants in refluxing THF. This operationally simple procedure provides the corresponding sulfides in excellent yields with only the formation of the neutral trichloroacetamide as the side product. The imidate may also be formed in situ, allowing for a direct method for the formation of sulfides from alcohols. This reaction provides a general method for the synthesis of a variety of sulfides from inexpensive and readily available alcohol starting materials.
Phosphabarrelenes as ligands in rhodium-catalyzed hydroformylation of internal alkenes essentially free of alkene isomerization
Fuchs, Evelyn,Keller, Manfred,Breit, Bernhard
, p. 6930 - 6939 (2007/10/03)
Despite significant research efforts in the past, one of the remaining problems to be solved in industrially important hydroformylation is the chemoselective low-pressure hydroformylation of internal alkenes. We report here on a new class of phosphabarrelene/rhodium catalysts 2 that display very high activity towards hydroformylation of internal alkenes with an unusually low tendency towards alkene isomerization. Preparation of new phosphabarrelene ligands, studies of their coordination properties, as well as results obtained in the rhodium-catalyzed hydroformylation of cyclic and acyclic internal alkenes are reported.
A synthesis of herboxidiene
Blakemore, Paul R.,Kocienski, Philip J.,Morley, Andrew,Muir, Kenneth
, p. 955 - 968 (2007/10/03)
The natural herbicide herboxidiene was constructed from two key fragments using a modified Julia olefination based on the benzothiazolyl sulfone activator. Key steps in the synthesis of the C1-C10 oxane fragment were (a) a modified Julia olefination using
