32063-84-6Relevant articles and documents
Synthesis of substituted aziridines via intramolecular reactions of β-N-chloroethylamino carbanions
Makosza, Mieczyslaw,Bobryk, Karolina,Krajewski, Dariusz
experimental part, p. 1511 - 1524 (2009/07/17)
Simple and efficient method of synthesis of 2-alkoxycarbonyl, 2-cyano, 2-phenylsulfonyl N-alkylaziridines was elaborated via intramolecular nucleophiles substitution of chloride in 1-N-chloro-2-alkoxycarbonyl (cyano, phenylsulfonyl) ethyl amines. These su
REACTION OF HYDROGEN FLUORIDE IN PYRIDINE SOLUTION WITH CIS-CYANO-2 AND CIS-AMIDO-2-AZIRIDINES. PREPARATION OF β-FLUORO α-AMINO ACIDS AND ESTERS BY MEANS OF ACID HYDROLYSIS AND ALCOHOLYSIS OF β-FLUORO-α-AMINONITRILES AND/OR β-FLUORO-α-AMINO ACID AMIDES
Ayi, Ayicoue,Guedj, Roger
, p. 481 (2007/10/02)
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N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation
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, (2008/06/13)
Aziridine-2-carboxylic acid derivatives of the formula STR1 wherein X is a carboxyl, nitrile, alkoxycarbonyl or carbamoyl group, and R and R1 are various organic radicals, or pharmacologically acceptable salts thereof, exhibit marked immunostimulant activity, especially in conjunction with added chemotherapeutic agents such as a penicillin, a cephalosporin, a nitrofuran or chloramphenicol. Those compounds are new where X is a cyano group or an alkoxycarbonyl radical and R1 is a hydrogen atom, but R' is not an unsubstituted alkyl radical or an alkyl radical substituted by hydroxyl, alkoxy, dialkylamino, phenyl, 4-chlorophenyl or 4-methoxyphenyl or a vinyl radical substituted by a phenyl or methyl radical, or a cycloalkyl radical, a phenyl a 4-chlorophenyl, a 4-methoxyphenyl, an s-triazinyl or a pyridinyl radical; or where X is a carbamoyl group and R1 is a hydrogen atom, R' is not an unsubstituted cyclohexyl, alkyl or benzyl radical; or where X is a cyano group or an alkoxycarbonyl radical and R1 is a phenyl radical, R' is not an isopropyl, cyclohexyl, phenyl, benzyl or p-chlorobenzyl radical; or where R1 is a methyl radical, R1 is not a benzyl, p-chloro- or p- methoxybenzyl radical.