3207-12-3

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-AMINO-2-METHYL-1-PROPANOL HYDROCHLORIDE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals due to its versatile chemical properties and reactivity.
Used in Solvent Applications:
AMPH hydrochloride is used as a solvent in various chemical processes and reactions, providing a medium for the dissolution and interaction of different compounds.
Used in Corrosion Inhibition:
2-AMINO-2-METHYL-1-PROPANOL HYDROCHLORIDE is used as a corrosion inhibitor to protect metal surfaces from degradation and wear in industrial settings.
Used as a pH Regulator:
AMPH hydrochloride is used to regulate the pH of various solutions, ensuring optimal conditions for chemical reactions and processes.
Used in Surfactant and Detergent Production:
2-AMINO-2-METHYL-1-PROPANOL HYDROCHLORIDE is used as an intermediate in the production of surfactants and detergents, contributing to their emulsifying, cleaning, and dispersing properties.
Used in Emulsifier and Lubricant Production:
AMPH hydrochloride is used in the production of emulsifiers and lubricants, enhancing the stability and performance of these products in various applications.
Safety and Storage:
2-AMINO-2-METHYL-1-PROPANOL HYDROCHLORIDE is considered relatively safe for use in industrial and laboratory settings. However, it should be handled with care and stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability and effectiveness.

InChI:InChI=1/C10H14N5O7P.ClH/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1H/t4-,6-,7-,10-;/m1./s1

Upstream product

• 58004-55-0 N-(1-cyano-1-methyl-ethyl)formamide 
• 682-85-9 N-(1-hydroxy-2-methylpropan-2-yl)formamide 
• 107892-41-1 isobutyl 2,2,2-trichloroacetimidate 

Downstream Products

• 3539-92-2 2-amino-1-benzoyloxy-2-methyl-propane; hydrochloride 
• 17199-19-8 β-Hydroxy-tert-butyl-trimethylammonium-iodid 

Relevant academic research and scientific papers

PROCESS FOR PRODUCING SUBSTITUTED AMINO ALCOHOLS

The present invention relates to a process for producing a compound of the formula (I) comprising at least the process step: a) reacting a compound of the formula (II) with hydrogen and water in the presence of at least one homogeneous transition metal catalyst TMC 1.

Ruthenium-Catalyzed Deaminative Hydrogenation of Amino Nitriles: Direct Access to 1,2-Amino Alcohols

A new approach for the efficient and highly selective synthesis of 1,2-amino alcohols by direct reductive hydrolysis of N-formyl-protected α-amino nitriles is reported. The commercially available RuHCl(CO)(PPh3)3 complex was found to be a suitable catalyst for this operationally simple protocol, in which no stoichiometric amounts of undesired metal waste are generated. The deaminative hydrogenation is performed at 55 bar of H2, using a 6:1 mixture of 1,4-dioxane/water as solvent. In addition, hydroxymethyl alcohols were prepared from cyanoketones under very similar conditions.

Radical-mediated intramolecular β-C(sp3)-H amidation of alkylimidates: Facile synthesis of 1,2-amino alcohols

A new radical-mediated intramolecular β-C(sp3)-H amidation reaction of O-alkyl trichloro- or arylimidates is reported. Various oxazolines were efficiently prepared from easily accessible alcohol starting materials. The trichloro-oxazoline products can be hydrolyzed under mild conditions to give valuable 1,2-amino alcohols. This amidation reaction exhibits a broad substrate scope and good functional group tolerance, and offers a powerful means for the C(sp3)-H functionalization of alcohols. Mechanistic studies suggest that a sequence of 1,5-HAT of an imidate radical, iodination and cyclization might be operative.

Carbacyclin analogs

Carbacyclin analogs that exhibit platelet aggregation inhibition activity and other biological activites common to structurally related prostacyclins are provided.