320740-32-7Relevant academic research and scientific papers
The synthesis of C2-symmetric and axially chiral compounds for recognition and catalysis
Clews, John,Curtis, Anthony D.M.,Malkin, Hugh
, p. 8735 - 8746 (2000)
Axially chiral amidines and guanidines, some possessing C2-symmetry, have been targeted as potential chiral catalysts for reactions of α,β-unsaturated carboxylic acids or esters. The key step in each synthesis required the coupling of two sterically demanding aromatic compounds to form atropisomeric biaryl species. (C) 2000 Elsevier Science Ltd.
CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
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, (2015/03/13)
Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
