32077-87-5Relevant articles and documents
ENZYMIC SYNTHESIS OF CHEMICALLY UNSTABLE CARDIAC GLYCOSIDES BY β-GALACTOSIDASE FROM ASPERGILLUS ORYZAE
Ooi, Yasuhiro,Hasimoto, Toshihiro,Mitsuo, Naoki,Satoh, Toshio
, p. 2241 - 2244 (1984)
β-Galactosidase obtained from Asp. oryzae was found to have strong transglycosylation activity.The glycosylation of water soluble and insoluble alcohols was successfully performed under such mild conditions at pH 5 at 4-37 deg C by using the enzyme.This enzymic method was applied to the one step synthesis of several cardiac glycosides difficult to obtain by ordinary chemical methods.
Enzymic Formation of β-Alkyl Glycosides by β-Galactosidase from Aspergillus oryzae and Its Application to the Synthesis of Chemically Unstable Cardiac Glycosides
Ooi, Yasuhiro,Hashimoto, Toshihiro,Mitsuo, Naoki,Satoh, Toshio
, p. 1808 - 1814 (2007/10/02)
β-Galactosidase obtained from Aspergillus oryzae was found to have strong transglycosylation activity.The glycosylation of water-soluble and insoluble alcohols was successfully performed under mild conditions (pH 5 at 4-37 deg C) with this enzyme.The enzyme was also applied to the one-step synthesis of several cardiac glycosides that are difficult to obtain by ordinary chemical methods.Keywords--enzymic transglycosylation; β-galactosidase; Aspergillus oryzae; cardiac glycoside; alkyl β-glycoside
