32116-30-6Relevant academic research and scientific papers
Reaction of α-benzenesulfonylphenylacetic acid with alkyl halides. Decarboxylative alkylation vs. decarboxylative protonation
Wladislaw, Blanka,Perna, Fernando,De Almeida Neves, Regina Maria,Marzorati, Liliana,Di Vitta, Claudio
, p. 1403 - 1409 (2004)
The reaction of α-benzenesulfonylphenylacetic acid with some alkyl halides, using as base NaH in DMSO, leads to decarboxylative protonation to give benzylphenylsulfone. Decarboxylative alkylation occurs only when CO2 is expelled by flushing with nitrogen. The mechanism of the decarboxylative protonation is investigated.
