70683-04-4

Basic information

• Product Name: phenyl(phenylsulfonyl)acetic acid
• CAS NO: 70683-04-4
• Molecular Formula: C₁₄H₁₂O₄S
• Molecular Weight: 276.3077
• Mol File: 70683-04-4.mol

Chemical Properties

• Boiling Point: 507.5°C at 760 mmHg
• Flash Point: 260.7°C
• Density: 1.355g/cm³
• Vapor Pressure: 4.04E-11mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: phenyl(phenylsulfonyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl(phenylsulfonyl)acetic acid(70683-04-4)
• EPA Substance Registry System: phenyl(phenylsulfonyl)acetic acid(70683-04-4)

Safety Data

• Hazardous Substances Data: 70683-04-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Phenyl(phenylsulfonyl)acetic acid is used as a building block for the synthesis of various organic compounds. Its unique structural features and reactivity make it a valuable component in the creation of new molecules.
Used in Pharmaceutical Research:
Phenyl(phenylsulfonyl)acetic acid is used as a starting material in the development of drugs and bioactive molecules. Its potential applications in medicinal chemistry are being explored due to its ability to form esters and amides, which are important in the design of pharmaceutical agents.
Used in Drug Development:
Phenyl(phenylsulfonyl)acetic acid is used as a precursor in the synthesis of drug candidates. Its acidic properties and ability to form esters and amides contribute to its utility in the creation of new therapeutic agents.
Used in Medicinal Chemistry:
Phenyl(phenylsulfonyl)acetic acid is used as a key intermediate in the synthesis of bioactive molecules. Its potential applications in the field of medicinal chemistry are being investigated, with a focus on its role in the development of novel therapeutic agents.

Upstream product

• 10490-07-0 2-phenyl-2-(phenylthio)acetic acid 
• 876494-48-3 benzenesulfinyl-phenyl-acetic acid 
• 124-38-9 carbon dioxide 
• 3112-88-7 Benzyl phenyl sulfone 
• 108-98-5 thiophenol 
• 4755-72-0 Chloro-phenyl-acetic acid 
• 321038-73-7 (S)-2-phenyl-2-(phenylthio)acetic acid 
• 1121-53-5 benzyl sodium 
• 930-69-8 sodium thiophenolate 
• 7417-81-4 benzyl phenyl sulfoxide 
• 945-51-7 1,1'-sulfinylbisbenzene 

Downstream Products

• 102677-59-8 α-methylsulfanylbenzyl phenylsulfone 
• 33641-51-9 [(phenylmethyl-d₂)sulfonyl]benzene 
• 24422-78-4 phenyl α-methylbenzyl sulfone 
• 1067227-35-3 C₂₀H₂₀O₄S 
• 32116-30-6 benzylphenylsulfone carbanion 
• 95158-93-3 1,2-diphenylethyl phenyl sulfone 
• 3112-88-7 Benzyl phenyl sulfone 
• 15296-88-5 ((bromo(phenyl)methyl)sulfonyl)benzene 

Relevant articles and documents

COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT

The present disclosure provides compositions including a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions

Selective synthesis of sulfoxides and sulfones from sulfides using silica bromide as the heterogeneous promoter and hydrogen peroxide as the terminal oxidant

Silica bromide as a heterogeneous promoter and reagent is prepared from the reaction of silica gel with PBr3as a non-hydroscopic, filterable, cheap, and stable yellowish powder that can be stored for months. The results show that silica bromide is a suitable and efficient promoter for the chemoselective oxidation of sulfides to the corresponding sulfoxides or sulfones in the presence of 30% H2O2in acetonitrile. The excellent yields, heterogeneous conditions, simplicity, compatibility with a variety of functionalities, and ease of isolation of the products make our procedure a practical alternative.

Decarboxylative allylation using sulfones as surrogates of alkanes

(Chemical Equation Presented) α-Sulfonyl functional groups are traceless activating groups that facilitate catalytic decarboxylative allylations in high yield yet can be cleaved to allow the synthesis of simple allylated alkanes. Substrate studies suggest