32121-06-5Relevant articles and documents
Kopecky,Grover
, p. 3153,3164 (1969)
Palladium-catalyzed intramolecular decarboxylative coupling of arene carboxylic acids/esters with aryl bromides
Shen, Zengming,Ni, Zhenjie,Mo, Song,Wang, Jing,Zhu, Yamin
supporting information; experimental part, p. 4859 - 4865 (2012/06/04)
Give me a ring? An efficient approach has been developed for the intramolecular decarboxylative coupling of arene carboxylic acids/esters with aryl bromides catalyzed by palladium (see scheme). From a synthetic viewpoint, this method is highly attractive because the catalyst loading is low, the optimized reaction conditions are mild, and the substrate scope is broad. Copyright
Fluorinated pentene diamine derivatives
-
, (2008/06/13)
Fluorinated alkenylene diamine compounds are inhibitors of ornithine decarboxylase enzyme in vivo and have the following formula: STR1 wherein: Ra represents hydrogen or R2, where R2 is as defined below; Rb represents hydrogen or, when Ra is hydrogen, R2, where R2 is as defined below; Rc represents hydrogen or --COR3, where R3 is as defined below; R1 represents hydrogen or C1 --C6 alkyl; each R2, independently, represents C2 -C5 alkylcarbonyl, phenylcarbonyl, phenyl-(C1 -C4 alkyl) carbonyl, or an aminocarboxylic acid residue derived by removal of an hydroxy group from a carboxy moiety of an L-aminocarboxylic acid; R3 represents hydroxy, or, when Ra and Rb are both hydrogen, C1 -C8 alkoxy, --NR4 R5, where R4 and R5 are as defined below, or an aminocarboxylic acid residue derived by removal of an hydrogen atom from the amino moiety of an L-aminocarboxylic acid; R4 and R5, independently, represent hydrogen or C1 -C4 alkyl; and p represents 1 or 2.