321309-33-5

Basic information

• Product Name: 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE
• Synonyms: 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE;Isoxazole, 3-isothiocyanato-5-methyl- (9CI);3-isothiocyanato-5-methyl-1,2-oxazole
• CAS NO: 321309-33-5
• Molecular Formula: C₅H₄N₂OS
• Molecular Weight: 140.16
• Product Categories: ISOTHIOCYANATE
• Mol File: 321309-33-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 284.5°Cat760mmHg
• Flash Point: 125.9°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 0.00508mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE(321309-33-5)
• EPA Substance Registry System: 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE(321309-33-5)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2811
• Hazardous Substances Data: 321309-33-5(Hazardous Substances Data)

Usage

General Description

5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE is a chemical compound with the molecular formula C7H6N2OS. It is a derivative of isothiocyanate and isoxazole, containing a methyl group at the 5-position of the isoxazole ring. 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE is used in the synthesis and research of various organic compounds and pharmaceuticals. It is known for its potential applications in the development of new drugs and bioactive molecules due to its unique structure and properties. 5-METHYL-3-ISOXAZOLYL ISOTHIOCYANATE is also used as a reagent in chemical reactions for the production of diverse organic compounds.

InChI:InChI=1/C5H4N2OS/c1-4-2-5(6-3-9)7-8-4/h2H,1H3

Upstream product

• 1105025-90-8 C₁₀H₈N₄O₂S₂ 
• 1072-67-9 5-methylisoxazol-3-ylamine 
• 463-71-8 thiophosgene 

Downstream Products

• 443111-15-7 C₁₁H₁₀ClN₃OS 
• 579495-28-6 C₁₃H₁₅N₃O₂S 
• 443111-03-3 C₁₂H₁₂ClN₃OS 
• 443110-99-4 C₁₁H₁₀FN₃OS 
• 1275515-50-8 C₁₂H₉ClF₃N₃OS 
• 443110-87-0 C₁₂H₁₃N₃O₂S 
• 443110-91-6 C₁₁H₁₀ClN₃OS 
• 443111-46-4 C₁₂H₁₃N₃OS 
• 443111-58-8 C₁₂H₁₃N₃O₂S 
• 110196-91-3 C₁₂H₁₁N₃O₂S 
• 1329497-57-5 C₁₃H₁₅N₃O₂S 

Relevant articles and documents

Dimer of 5-methyl-3-isoxazolyl isothiocyanate

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4-Chlorocolchicine derivatives bearing a thiourea side chain at the C-7 position as potent anticancer agents

A series of 4-substituted colchicine derivatives were synthesized and evaluated with an eye toward developing new anticancer agents. As a result, 4-chlorocolchicine derivatives bearing a thioureide side chain at the C-7 position were found to exhibit significant cytotoxicities to three human cancer cell lines (A549, HT-29, and HCT116). In particular, compound 26 having an ethylthioureide group at the C-7 had high antitumor activity in vivo and a broad effective dosage range. Furthermore, compound 58, which has a (5-methylpyrazol-3-yl)thioureide group at the C-7 side chain, exhibited strong cytotoxicity and desirable metabolic stability in vitro.

Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors: Approach to creation of bioavailable drugs

Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors were synthesized and identified. Their ability to inhibit the glutamate stimulated Ca uptake was measured. Permeation experiments on the phospholipid membranes were conducted, and the apparent