110196-91-3Relevant academic research and scientific papers
1-(5-(R-Amino)-1,2,4-thiadiazol-3-yl)propan-2-ones: Convenient ketomethylenic reagents for the gewald and dimroth reactions
Pokhodylo, Nazariy T.,Shyyka, Olga Ya.
, p. 1487 - 1490 (2015)
1-(5-(R-Amino)-1,2,4-thiadiazol-3-yl)propan-2-ones were used as activated ketomethylenic compounds for the Gewald and Dimroth reactions. It was found out that they exhibited high reactivity in such anion reactions for the construction of the 1,2,3-triazol
Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors: Approach to creation of bioavailable drugs
Perlovich, German L.,Proshin, Alexey N.,Volkova, Tatyana V.,Petrova, Ludmila N.,Bachurin, Sergey O.
experimental part, p. 2156 - 2167 (2012/10/08)
Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors were synthesized and identified. Their ability to inhibit the glutamate stimulated Ca uptake was measured. Permeation experiments on the phospholipid membranes were conducted, and the apparent
