32133-72-5Relevant academic research and scientific papers
One-Pot Reaction of Carboxylic Acids and Ynol Ethers for the Synthesis of β-Keto Esters
Zeng, Linwei,Lai, Zhencheng,Cui, Sunliang
, p. 14834 - 14841 (2018)
An one-pot reaction of carboxylic acids and ynol ethers for the synthesis of β-keto esters has been developed. Under promotion of Ag2O, various carboxylic acids and ynol ethers could transform to α-acyloxy enol esters, which undergo a following DMAP-catalyzed rearrangement to deliver β-keto esters rapidly. This method provides a direct approach to β-keto esters from carboxylic acids without any preactivation. The protocol features mild reaction conditions, broad substrate scope, and the products could be transformed to an array of compounds.
Multicomponent Synthesis of Tetrahydroisoquinolines
Zeng, Linwei,Huang, Bo,Shen, Yangyong,Cui, Sunliang
supporting information, p. 3460 - 3464 (2018/06/26)
A multicomponent synthesis of tetrahydroisoquinolines from carboxylic acids, alkynyl ethers, and dihydroisoquinolines is described. This process features readily available starting materials, simple experimental procedures for achievement of molecule comp
Silver-catalyzed regio- and stereoselective addition of carboxylic acids to ynol ethers
Yin, Jing,Bai, Yihui,Mao, Mengyi,Zhu, Gangguo
, p. 9179 - 9185 (2015/02/19)
A silver-catalyzed trans addition of carboxylic acids to ynol ethers is described. The reaction has a broad scope with respect to carboxylic acids and ynol ethers, delivering (Z)-α-alkoxy enol esters in good yields with excellent regio- and stereoselectiv
