321380-35-2

Upstream product

• 273400-77-4 4-methoxyphenyl 3,4,6-tri-O-acetyl-2-deoxy-2-trichloroacetamido-β-D-glucopyranoside 
• 273400-79-6 4-methoxyphenyl 2-deoxy-2-trichloroacetamido-β-D-glucopyranoside 
• 100-39-0 benzyl bromide 
• 321380-33-0 4-methoxyphenyl 4,6-O-benzylidene-2-deoxy-2-trichloroacetamido-β-D-glucopyranoside 

Downstream Products

• 321380-47-6 methyl (4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranosyl)-(1->4)-(methyl 2-O-benzoyl-3-O-benzyl-α-L-idopyranosid)uronate 
• 321380-51-2 methyl (2-acetamido-4-O-acetyl-3,6-di-O-benzyl-2-deoxy-β-D-galactopyranosyl)-(1->4)-(methyl 2-O-benzoyl-3-O-benzyl-α-L-idopyranosid)uronate 
• 321380-67-0 (2R,3S,4R,5R,6R)-3-((2S,3R,4R,5R,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-4-benzyloxy-5-hydroxy-6-methoxy-tetrahydro-pyran-2-carboxylic acid 
• 321380-43-2 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-1-O-trichloroacetimidoyl-α-D-galactopyranose 
• 321380-41-0 4-methoxyphenyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside 
• 321380-39-6 4-methoxyphenyl 3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside 
• 321380-37-4 4-methoxyphenyl 3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-β-D-glucopyranoside 

Relevant academic research and scientific papers

Syntheses of β-D-GalpNAc4SO3-(1→4)-L-IdopA2SO3, a disaccharide fragment of dermatan sulfate, and of its methyl α-L-glycoside derivative

The syntheses of sodium (sodium 2-acetamido-2-deoxy-4-O-sulfonato-β-D-galactopyranosyl)-(1→4)-(sodium 2-O-sulfonato-L-idopyran)uronate, a disaccharide fragment of dermatan sulfate, and of its methyl α-L-glycoside derivative are reported for the first time. The use of 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-trichloroacetamido-1-O-trichloroaceti midoyl-α-D-galactopyranose, readily prepared from a D-gluco precursor, allowed the stereocontrolled and high yielding coupling with the low reactive 4-hydroxyl group of L-iduronic acid ester derivatives. Classical transformation of the disaccharide products into the target molecules was achieved in high yield. (C) 2000 Elsevier Science Ltd.