321385-93-7 Usage
Property
Chemical compound
Property
Belongs to the class of pyrazole amines
Property
Potent and selective Bruton's tyrosine kinase (BTK) inhibitor
Property
Promising drug candidate for treatment of autoimmune diseases and B-cell malignancies
Property
Inhibition of BTK suppresses activation and proliferation of B cells
Property
Currently undergoing further clinical development for safety and efficacy evaluation.
Content
Also known as Rilzabrutinib
Content
Shown potential in preclinical and clinical studies for rheumatoid arthritis, multiple sclerosis, and chronic lymphocytic leukemia
Check Digit Verification of cas no
The CAS Registry Mumber 321385-93-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,1,3,8 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 321385-93:
(8*3)+(7*2)+(6*1)+(5*3)+(4*8)+(3*5)+(2*9)+(1*3)=127
127 % 10 = 7
So 321385-93-7 is a valid CAS Registry Number.
321385-93-7Relevant academic research and scientific papers
Metal-free ring opening of 5-amino-1,4-diaryl-1H-pyrazoles: A facile access to 2-aryl-3-arylazoacrylonitriles
Bandyopadhyay, Debashruti,Chatterjee, Arpita,Kanchithalaivan, Selvaraj,Peruncheralathan, Saravanan,Radhakrishnan, Divya
supporting information, (2022/01/20)
Various 2-aryl-3-arylazoacrylonitriles are synthesized while attempting the intramolecular N-arylation of 5-aminopyrazoles, using the hypervalent iodine reagent. The synthesis involves phenyl iodine diacetate-assisted ring opening of 5-aminopyrazoles at r
