3215-37-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Acetylcarbazole is used as an active pharmaceutical ingredient for its antimicrobial and antitumor properties. It plays a crucial role in the development of new drugs that target various diseases and conditions.
Used in Agrochemical Industry:
3-Acetylcarbazole is used as a key intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye and Pigment Synthesis:
3-Acetylcarbazole is used as a precursor in the synthesis of various dyes and pigments due to its ability to undergo chemical reactions such as acylation and halogenation. This makes it a valuable component in the production of colorants for various applications.
Used in Organic Synthesis:
3-Acetylcarbazole is used as a versatile building block in organic synthesis, enabling the creation of a wide range of compounds for various industries, including pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C14H11NO/c1-9(16)10-6-7-14-12(8-10)11-4-2-3-5-13(11)15-14/h2-8,15H,1H3

Upstream product

• 574-39-0 9-acetylcarbazole 
• 56759-32-1 1-(4-amino-3-bromophenyl)-ethanone 
• 91901-93-8 2-azido-5-methyl-1,1'-biphenyl 

Downstream Products

• 92855-55-5 1-(3-acetyl-carbazole-9-yl)ethanone 
• 1484-05-5 1-(9-methyl-9H-carbazol-3-yl)ethanone 
• 5599-49-5 3-ethyl-9H-carbazole 
• 51035-17-7 9H-carbazole-3-carboxylic acid 
• 374916-11-7 5,6,7,8-Tetrahydrocarbazol-3-essigsaeure 

Relevant academic research and scientific papers

Visible-light-promoted intramolecular C-H amination in aqueous solution: Synthesis of carbazoles

An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.

Palladium-Catalyzed Intramolecular C–H Amination in Water

Palladium(II) catalysis was found to be effective for intramolecular C–H amination in water. With 2-azidobiphenyls as substrates, the reaction efficiently provided various carbazoles with N2as the sole byproduct. The reaction showed high functional-group tolerance and could be used in the synthesis of several natural carbazole alkaloids. The catalytic process was promoted by water, and the reaction was inefficient in the organic solvents that were investigated.

Photoanilid-analoge Umlagerungen von N-Acyl-Derivaten des 5H-Benzocarbazols

The known photo rearrangement of N-acetylcarbazole yielding carbazole ketones has also been observed for the N-acetyl and N-(2-naphthoyl) derivatives 3, 4 of 5H-benzocarbazole (8), whereas N-(2-naphthoyl)carbazole (2) is photochemically almost stable.An explanation for this different behaviour on the basis of the term schemes of the compounds studied is suggested.