5599-49-5Relevant academic research and scientific papers
Dearomatization-Rearomatization Strategy for Synthesizing Carbazoles with 2,2′-Biphenols and Ammonia by Dual C(Ar)-OH Bond Cleavages
Cao, Dawei,Yu, Jing,Zeng, Huiying,Li, Chao-Jun
, p. 13200 - 13205 (2020/12/18)
Carbazole is an essential building block in various pharmaceuticals, agrochemicals, natural products, and materials. For future sustainability, it is highly desirable to synthesize carbazole derivatives directly from renewable resources or cheap raw materials. Phenolic compounds are a class of degradation products of lignin. On the other hand, ammonia is a very cheap industrial inorganic chemical. Herein, an efficient dearomatization-rearomatization strategy has been developed to directly cross-couple 2,2′-biphenols with ammonia by dual C(Ar)-OH bond cleavages. This strategy provides a greener pathway to synthesize valuable carbazole derivatives from phenols.
One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides under metal-free conditions
Xiao, Fuhong,Liao, Yunfeng,Wu, Mingyue,Deng, Guo-Jun
supporting information, p. 3277 - 3280 (2013/01/16)
One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides is disclosed. Various substituted carbazoles were obtained in moderate to good yields via a sequence of condensation, cyclization and dehydrogenation under metal free conditions using molecular oxygen as an oxidant.
Synthesis of carbazoles from o-cyclohex-2-enylanilines
Majumdar,Das,Kundu
, p. 1593 - 1600 (2007/10/03)
Several carbazoles (4a-f) have been synthesised from o-cyclohex-2- enylanilines by treatment with pyridine hydrotribromide in methylene chloride at 05 °C for 2 h followed by refluxing with Pd-C in diphenyl ether for 1 h.
