32151-01-2 Usage
Uses
Used in Pharmaceutical Industry:
(1R,2S)-(+)-2-Amino-1-indanol hydrochloride is used as an intermediate in the synthesis of various pharmaceuticals for its versatile chemical reactivity and potential therapeutic properties. Its chiral nature and specific stereochemistry make it a valuable component in the development of enantiomerically pure drugs, which can exhibit different biological activities and reduce potential side effects.
Used in Organic Synthesis:
(1R,2S)-(+)-2-Amino-1-indanol hydrochloride is used as a building block in organic synthesis for the preparation of complex organic molecules and compounds. Its functional groups, such as the amino and hydroxyl groups, allow for a wide range of chemical reactions, making it a useful precursor in the synthesis of various organic compounds with potential applications in different industries.
Used in Drug Development:
(1R,2S)-(+)-2-Amino-1-indanol hydrochloride is used as a lead compound in drug discovery and development due to its biological activity and potential therapeutic use. Its unique stereochemistry and functional groups enable the design and optimization of new drugs with improved efficacy and selectivity, contributing to the advancement of novel therapeutic agents for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 32151-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,1,5 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32151-01:
(7*3)+(6*2)+(5*1)+(4*5)+(3*1)+(2*0)+(1*1)=62
62 % 10 = 2
So 32151-01-2 is a valid CAS Registry Number.
32151-01-2Relevant academic research and scientific papers
Efficient diastereoselective synthesis of cis-2-amino-1-indanol derivatives and cis- and trans-1-amino-2-indanol via Pd-catalyzed hydrogenation
Nguyen, Thi Ha,Ma, Eunsook
supporting information, p. 3717 - 3728 (2021/11/01)
(±)-cis-2-amino-1-indanol was diastereoselectively synthesized from 1,2-indanedion-2-oxime in ethanol at 25 °C under 10% Pd/C-catalyzed hydrogenation conditions. Under the same hydrogenation condition, 1,2-indanedion-2-oxime and their derivatives having one and/or two electron-donating groups in aliphatic or aromatic part of indanyl ring were diastereoselectively reduced to racemic cis-2-amino-1-indanol derivatives. From 1,2-indanedion-1-oxime, (±)-trans-1-amino-2-indanol was obtained in ethanol at 25 °C over a 10% Pd/BaSO4 catalyst. In contrast, the 10% Pd/BaSO4-catalyzed hydrogenation reaction in ethanol at 45 °C afforded cis-1-hydroxyamino-2-indanol from 1,2-indanedion-1-oxime, followed by reduction to form (±)-cis-1-amino-2-indanol. The diastereoselectivity of β-aminoindanols was dependent on the Pd catalyst, reaction temperature, and pH of the reaction medium.
