321526-75-4Relevant academic research and scientific papers
Synthesis of substituted tetrahydroisoquinolines and benzo[d]azepines from phthalan or isochroman and N-silylaldimines
Foubelo,Gomez,Gutierrez,Yus
, p. 1061 - 1064 (2007/10/03)
The 4,4'-di-tert-butylbiphenyl-catalyzed lithiation of phthalan (1a) and isochroman (1b) in THF at 0°C affords the corresponding functionalized benzyllithiums 2, which by reaction with N-silylaldimines yield, after acid-base work-up, the expected amino al
