32164-02-6 Usage
Uses
Used in Pharmaceutical Industry:
D-erythro-sphinganine (C17 base) is used as an antifungal agent for its ability to inhibit the growth of Candida glabrata and Candida albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. This makes it a promising candidate for the development of new antifungal treatments.
Used in Diagnostics:
D-erythro-sphinganine (C17 base) is used as a biomarker for the assessment of delayed-type hypersensitivity and response to triptolide. Its role in diagnostics aids in the evaluation of immune system responses and the effectiveness of certain therapeutic interventions.
Used in Analytical Chemistry:
D-erythro-sphinganine (C17 base) is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods. Its consistent and reliable performance enhances the accuracy and precision of these analytical techniques, contributing to the advancement of research in sphingolipid biology and related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 32164-02-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,1,6 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 32164-02:
(7*3)+(6*2)+(5*1)+(4*6)+(3*4)+(2*0)+(1*2)=76
76 % 10 = 6
So 32164-02-6 is a valid CAS Registry Number.
32164-02-6Relevant academic research and scientific papers
So, Regina C.,Ndonye, Rachel,Izmirian, Douglas P.,Richardson, Stewart K.,Guerrera, Robyn L.,Howell, Amy R.
, p. 3233 - 3235 (2004)
Sphinganines can be synthesized in just three steps from easily prepared serine-derived Weinreb amide 4. Pre-deprotonation of the acidic (N-H and O-H) protons of 4 allows for its efficient conversion to amino ketones 5. Such ketones can be selectively reduced to either erythro- or threo-sphinganines. Partially protected sphinganines 11 are also readily accessible in five steps from 4. Thus, Weinreb amide 4 represents one of the most versatile templates described to date for sphinganine synthesis.
