321689-96-7 Usage
Uses
Used in Pharmaceutical Industry:
1-allyl-3-(pyridin-4-yl)thiourea is used as a selective inhibitor of thyroid peroxidase for the treatment of hyperthyroidism and Graves' disease. Its ability to inhibit the enzyme involved in thyroid hormone synthesis helps regulate hormone levels and alleviate symptoms associated with these conditions.
Used in Autoimmune and Inflammatory Disease Treatment:
1-allyl-3-(pyridin-4-yl)thiourea is used as an anti-inflammatory and immunosuppressive agent for the management of certain autoimmune and inflammatory diseases. Its properties to modulate the immune system and reduce inflammation can potentially alleviate symptoms and improve the quality of life for patients suffering from these conditions.
Used in Cancer Prevention and Treatment:
1-allyl-3-(pyridin-4-yl)thiourea is used as a potential chemopreventive and therapeutic agent for certain types of cancer. Its ability to modulate various signaling pathways and exhibit anti-proliferative effects on cancer cells suggests its potential use in cancer prevention and treatment strategies. Further research is required to explore its full potential and optimize its application in oncology.
Used in Scientific Research:
1-allyl-3-(pyridin-4-yl)thiourea is used as a research tool to study the role of thyroid peroxidase in thyroid hormone synthesis and its involvement in various physiological and pathological processes. Additionally, it serves as a valuable compound for investigating the mechanisms of action of anti-inflammatory and immunosuppressive agents, as well as their potential applications in the prevention and treatment of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 321689-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,1,6,8 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 321689-96:
(8*3)+(7*2)+(6*1)+(5*6)+(4*8)+(3*9)+(2*9)+(1*6)=157
157 % 10 = 7
So 321689-96-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11N3S/c1-2-5-11-9(13)12-8-3-6-10-7-4-8/h2-4,6-7H,1,5H2,(H2,10,11,12,13)
321689-96-7Relevant academic research and scientific papers
Synthesis and biological evaluation of arylthiourea derivatives with antitubercular activity
Luo, Rusong,Laitinen, Tuomo,Teng, Liyan,Nevalainen, Tapio,Lahtela-Kakkonen, Maija,Zheng, Baofu,Wang, Honghai,Poso, Antti,Zhang, Xuelian
, p. 640 - 650 (2013/08/23)
Tuberculosis (TB) is a contagious disease caused by Mycobacterium tuberculosis (M. tuberculosis), and remains one of the most life-threatening plagues for public health in the world. The emergence of drug resistant strains of TB and co-infection with HIV has further complicated TB treatment. Here, the synthesis and characterizaton of a series of compounds were described, and these were followed by evaluating for their antibacterial activity against M. tuberculosis. Several novel arylthiourea derivatives exhibited excellent activity (lowest MIC=0.09 μg/ml) against M. tuberculosis including drug resistant strains of M. tuberculosis. The results suggest that these compounds are promising candidates for new anti-TB agent development.
