3217-92-3Relevant academic research and scientific papers
Chemoselective Synthesis of Amines from Ammonium Hydroxide and Hydroxylamine in Continuous Flow
Audubert, Clément,Bouchard, Alexanne,Mathieu, Gary,Lebel, Hélène
, p. 14203 - 14209 (2019/01/21)
The chemoselective amination of alkyl bromides and chlorides with aqueous ammonia and hydroxylamine was achieved in continuous flow to produce primary ammonium salts and hydroxylamines in high yields. An in-line workup was designed to isolate the corresponding primary amine, which was also telescoped in further reactions, such as acylation and Paal-Knorr pyrrole synthesis. Monosubstituted epoxides are also compatible with the reaction conditions.
Metal- and Base-Free Room-Temperature Amination of Organoboronic Acids with N-Alkyl Hydroxylamines
Sun, Hong-Bao,Gong, Liang,Tian, Yu-Biao,Wu, Jin-Gui,Zhang, Xia,Liu, Jie,Fu, Zhengyan,Niu, Dawen
, p. 9456 - 9460 (2018/07/29)
We have found that readily available N-alkyl hydroxylamines are effective reagents for the amination of organoboronic acids in the presence of trichloroacetonitrile. This amination reaction proceeds rapidly at room temperature and in the absence of added metal or base, it tolerates a remarkable range of functional groups, and it can be used in the late-stage assembly of two complex units.
Primary hydroxylamines and uses thereof
-
Paragraph 0056; 0057; 0063, (2015/09/22)
The present invention relates to primary hydroxylamines, to pharmaceutical compositions comprising them, to their use in the treatment and/or prevention of bacterial infections and to their use in the prevention of formation or reduction of formed biofilm
A general one-pot, three-component mono N-alkylation of amines and amine derivatives in lithium perchlorate/diethyl ether solution
Heydari, Akbar,Tavakol, Hossein,Aslanzadeh, Saied,Azarnia, Jamshid,Ahmadi, Nafiseh
, p. 627 - 633 (2007/10/03)
An efficient, general procedure for reductive monoalkylation of amines and amine derivatives with aldehydes is reported. Treatment of aldehydes with primary amines, secondary amines, O-trimethylsilylhydroxylamine, and N,N-dimethylhydrazine in lithium perc
New NO donors with antithrombotic and vasodilating activities, Part 29. N-(1-cyanocyclohexyl)-C-phenylnitrones and glyoxaldinitrones.
Camehn,Rehse
, p. 130 - 134 (2007/10/03)
Six N-(1-cyanocyclohexyl)-C-phenylnitrones 4a-f (4b-f for the first time) and 22 glyoxaldinitrones 7a-v were prepared and tested for antithrombotic (p.o. administration to rats, 60 mg/kg) effects. Both classes of compounds exhibit considerable antithrombo
Enzyme-inhibiting amino acid derivatives, a process for the preparation thereof, agents containing these, and the use thereof
-
, (2008/06/13)
The present invention relates to compounds of the general formula I STR1 in which A denotes a radical from the group comprising S, SO, SO2, O, CO, CS or a direct bond, B denotes the radical of an amino acid and D denotes a CH2 group
