321719-29-3

Upstream product

• 4595-59-9 5-bromopyrimidine 
• 1354344-43-6 4-{(R)-7-(3,5-dichlorophenyl)-5-methyl-6-oxo-5-[[4-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]methyl]-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl}piperazine-1-carboxylic acid tert-butyl ester 
• 321657-07-2 (R)-5-(4-bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl chloride 
• 321657-64-1 4-[(R)-5-(4-bromobenzyl)-7-(3,5-dichlorophenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]piperazine-1-carboxylic acid tert-butyl ester 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Relevant academic research and scientific papers

Synthesis of potent lymphocyte function-associated antigen-1 inhibitors labeled with carbon-14 and deuterium, part 1

The lymphocyte function-associated antigen-1 (LFA-1) is an essential component in normal immune system function and is a target for drug discovery for its broad therapeutic potential in treating inflammatory diseases. Here, we report the synthesis of thre