321744-16-5 Usage
Uses
Used in Pharmaceutical Industry:
(1R,2R,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLO-PENTANE-4-CARBOXYLIC ACID METHYL ESTER is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of complex molecules with potential therapeutic applications.
Used in Synthesis of Stereoisomers:
(1R,2R,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLO-PENTANE-4-CARBOXYLIC ACID METHYL ESTER is used as a building block for the synthesis of stereoisomers of a tri-functionalized cyclopentane. These stereoisomers are valuable in pharmaceutical discovery, as they can exhibit different biological activities and properties, leading to the development of more effective drugs.
Used in Drug Delivery Systems:
In the field of drug delivery, (1R,2R,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLO-PENTANE-4-CARBOXYLIC ACID METHYL ESTER can be utilized to develop novel drug delivery systems. Its unique structure can be exploited to improve the delivery, bioavailability, and therapeutic outcomes of various pharmaceutical compounds.
Used in Chemical Research:
(1R,2R,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLO-PENTANE-4-CARBOXYLIC ACID METHYL ESTER is also used in chemical research for studying the properties and reactivity of compounds with similar structures. This can lead to a better understanding of their potential applications and the development of new synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 321744-16-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,1,7,4 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 321744-16:
(8*3)+(7*2)+(6*1)+(5*7)+(4*4)+(3*4)+(2*1)+(1*6)=115
115 % 10 = 5
So 321744-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H21NO5/c1-12(2,3)18-11(16)13-8-5-7(6-9(8)14)10(15)17-4/h7-9,14H,5-6H2,1-4H3,(H,13,16)/t7-,8+,9+/m0/s1
321744-16-5Relevant academic research and scientific papers
Use of hydrolases for the synthesis of cyclic amino acids
Lloyd, Richard C.,Lloyd, Michael C.,Smith, Mark E. B.,Holt, Karen E.,Swift, Jonathan P.,Keene, Philip A.,Taylor, Stephen J. C.,McCague, Raymond
, p. 717 - 728 (2007/10/03)
The synthesis of several cyclic amino acids that have all the necessary structural features to make them ideal scaffolds for use in medicinal chemistry is described. A key step in each synthesis is the use of hydrolase enzymes to define a chiral centre. I
Highly selective directed hydrogenation of enantiopure 4-(tert-butoxycarbonylamino)cyclopent-1-enecarboxylic acid methyl esters
Smith, Mark E.B.,Derrien, Nadine,Lloyd, Michael C.,Taylor, Stephen J.C.,Chaplin, David A.,McCague, Raymond
, p. 1347 - 1350 (2007/10/03)
The use of both N-tert-butoxycarbonylamino- and hydroxyl-directed hydrogenation methodology to yield essentially single diastereomers of 3-(tert-butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl esters and 3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid methyl esters is described. These results incorporate the first reported carbamate-directed hydrogenations of functionalised cyclopentenes.
An efficient route to all eight stereoisomers of a tri-functionalised cyclopentane scaffold for drug discovery
Smith, Mark E.B.,Lloyd, Michael C.,Derrien, Nadine,Lloyd, Richard C.,Taylor, Stephen J.C.,Chaplin, David A.,Casy, Guy,McCague, Raymond
, p. 703 - 705 (2007/10/03)
A route to all eight stereoisomers of 3-(tert-butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl ester is presented; these products should prove to be valuable scaffolds in pharmaceutical discovery.
