32176-94-6Relevant academic research and scientific papers
Seven-membered ring compound and application thereof in prevention and treatment of diabetes and metabolic syndrome
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, (2020/06/09)
The invention discloses a seven-membered ring compound and application thereof in prevention and treatment of diabetes and metabolic syndrome. The structure of the seven-membered ring compound is as shown in a general formula I, and definitions of substituent groups are as shown in the specification and claims. The seven-membered ring compound of the invention has an extremely excellent effect ofpreventing or treating diabetes and metabolic syndrome.
Diversity-Oriented Synthesis of Spiroannulated Benzofuran-3-one Scaffold of Leptosphaerin C and Congeners via Aryne Insertion
Dhokale, Ranjeet A.,Mhaske, Santosh B.
, p. 4875 - 4882 (2017/05/12)
A concise synthesis of functionalized cyclohexenone-fused spirobenzofuran-3-ones under mild reaction conditions was developed. The reaction proceeds via insertion of aryne into the C-O bond followed by a regioselective intramolecular conjugate addition. The use of silyl-protected acid was crucial for the transformation. This protocol was successfully applied for the synthesis of leptosphaerin C core and its novel analogues.
Triazole derivatives and pharmaceutical compositions comprising them
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Page/Page column 6, (2010/02/05)
The present invention relates to compounds of formula (I) and their pharmaccutically acceptable salts, solvates, hydrates and polymorphs. These compounds are powerful and selective CCK1 receptor agonists.
Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them
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Page 12; 13, (2010/02/06)
The invention relates to a compound of formula in which R1, X1, X2, X3, X4, R4, Y1, Y2 and Y3 are as defined in claim 1. These compounds are CCK-receptor agonists.
