321884-15-5

Basic information

• Product Name: 2H-Pyran, tetrahydro-2-(1-phenylpropoxy)-
• CAS NO: 321884-15-5
• Molecular Formula: C14H20O2
• Molecular Weight: 220.312
• Mol File: 321884-15-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2H-Pyran, tetrahydro-2-(1-phenylpropoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran, tetrahydro-2-(1-phenylpropoxy)-(321884-15-5)
• EPA Substance Registry System: 2H-Pyran, tetrahydro-2-(1-phenylpropoxy)-(321884-15-5)

Safety Data

• Hazardous Substances Data: 321884-15-5(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 93-54-9 1-Phenyl-1-propanol 

Downstream Products

• 93-54-9 1-Phenyl-1-propanol 
• 4426-82-8 (1-isothiocyanatopropyl)benzene 
• 93-55-0 1-phenyl-propan-1-one 

Relevant articles and documents

A highly efficient synthetic protocol for tetrahydropyranylation/ depyranylation of alcohols and phenols

Bismuth(III) nitrate pentahydrate [Bi(NO3)3· 5H2O] is found to be an effective catalyst for both tetrahydropyranylation and depyranylation of alcohols and phenols. Some of the major advantages of this protocol are: non-aqueous workup, good yields, the involvement of a less-expensive and nontoxic catalyst, and compatibility in the presence of a large number of other protecting groups. Notably, isopropylidene, benzylidene, and thioacetal groups are also unaffected under the experimental conditions. Remarkably, a selective mono-protection of diols and primary alcohols can be achieved chemoselectively by employing the same catalyst. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Parallel synthesis in an EOF-based micro reactor

We present herein a micro reactor set-up that enables parallel syntheses to be performed under electroosmotic flow conditions. The Royal Society of Chemistry.

Tetrabutylammonium tribromide (TBATB)-promoted tetrahydropyranylation/depyranylation of alcohols

Alcohols are tetrahydropyranylated rapidly in high yields in the presence of a catalytic amount of TBATB in dichloromethane at room temperature. Depyranylation to their parent alcohol is achieved in quantitative yields by merely changing the solvent to methanol.