321899-55-2

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 62-53-3 aniline 
• 109-72-8 n-butyllithium 
• 953-21-9 (1E,2E)-N,3-diphenylprop-2-en-1-imine 

Downstream Products

• 1394171-62-0 (E)-N-((E)-1-phenylhept-1-en-3-ylidene)aniline oxide 
• 1394171-62-0 (Z)-N-((E)-1-phenylhept-1-en-3-ylidene)aniline oxide 

Relevant academic research and scientific papers

A modular approach to α,β-unsaturated N-aryl ketonitrones

A modular approach to α,β-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting α,β-unsaturated imines provided N-allyl anilines, which were subjected to oxidation with

Electronic and steric control in regioselective addition reactions of organolithium reagents with enaldimines

A reaction mode of imines derived from naphthalene-1-carbaldehyde and acyclic α,β-unsaturated aldehydes with organolitium reagents was dependent on the characteristic nature of a substituent on the imine nitrogen atom. An imine having an electron-withdrawing aryl group on the nirtogen atom behaves as a 1,2-directing imine toward organolithium reagents. In contrast, an imine bearing an alkyl or a bulky aryl group favors 1,4-addition of organolithium reagents. Electronic and steric tuning of a substituent on the imine nitrogen atom for a reaction mode was rationalized on the basis of molecular orbital calculations.