32193-92-3Relevant academic research and scientific papers
Cyclization reactions involving palladium-catalyzed carbene insertion into aryl halides
Kudirka, Romas,Van Vranken, David L.
, p. 3585 - 3588 (2008)
(Chemical Equation Presented) Palladium is shown to catalyze the insertion of trimethylsilylmethylene into aryl halides, leading to benzylpalladium intermediates that cyclize to give indenylsilanes through carbopalladation of pendant alkenes or allenes. A
Rhodium-Catalyzed, Enantioselective Hydroacylation of ortho-Allylbenzaldehydes
Johnson, Kirsten F.,Schmidt, Adam C.,Stanley, Levi M.
supporting information, p. 4654 - 4657 (2015/10/12)
The development of a rhodium catalyst for endo- and enantioselective hydroacylation of ortho-allylbenzaldehydes is reported. A catalyst generated in situ from [Rh(COD)Cl]2, (R)-DTBM-SEGPHOS, and NaBARF promotes the desired hydroacylation reactions and minimizes the formation of byproducts from competitive alkene isomerization and ene/dehydration pathways. These rhodium-catalyzed processes generate the 3,4-dihydronaphthalen-1(2H)-one products in moderate-to-high yields (49-91%) with excellent enantioselectivities (96-99% ee).
