32229-98-4

Basic information

• Product Name: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol
• CAS NO: 32229-98-4
• Molecular Formula: C₁₃H₁₉ClN₂O
• Molecular Weight: 254.7558
• Mol File: 32229-98-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 408.6°C at 760 mmHg
• Flash Point: 200.9°C
• Density: 1.177g/cm³
• Vapor Pressure: 2.07E-07mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol(32229-98-4)
• EPA Substance Registry System: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol(32229-98-4)

Safety Data

• Hazardous Substances Data: 32229-98-4(Hazardous Substances Data)

Usage

General Description

3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-ol, also known as mCPP, is a psychoactive drug belonging to the phenylpiperazine class. It is often used in scientific research to study its effects on the central nervous system. mCPP acts as a serotonin and norepinephrine reuptake inhibitor, which means it interferes with the normal reabsorption of these neurotransmitters by nerve cells, leading to increased levels of serotonin and norepinephrine in the brain. This can result in various psychological and physiological effects, including changes in mood, anxiety, agitation, and increased heart rate. Due to its psychoactive properties, mCPP has been implicated in cases of drug abuse and overdose, and is regulated in some countries.

Upstream product

• 56968-29-7 1-(2-ethoxycarbonylethyl)-4-(3-chlorophenyl)-piperazine 

Downstream Products

• 39577-43-0 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine 
• 141473-81-6 4-(3-Chlorophenyl)-1-[3-(3,4-ethylenedioxyphenylcarbamoyloxy)propyl]piperazine, hydrochloride 
• 141473-58-7 4-(3-Chlorophenyl)-1-(3-[3,4,5-trimethoxyphenyl(thiocarbamoyl)oxy]propyl)piperazine, hydrochloride 
• 141473-75-8 4-(3-Chlorophenyl)-1-[3-(3,4-methylenedioxyphenylcarbamoyloxy)propyl]piperazine, hydrochloride 
• 103074-36-8 2-(2-(3-(4-(3-chlorophenyl)piperazino)propoxy)phenyl)-N-methylthiazolidine-3-thiocarboxamide 
• 103076-63-7 2-(3-(4-(3-chlorophenyl)piperazino)propoxy)benzaldehyde 

Relevant articles and documents

N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure

A piperazine derivative of the formula: STR1 wherein R1 is hydrogen, alkyl (C1-8), alkyl (C1-4)-sulfonyl or an acyl group of the formula: R3 CO--(wherein R3 is hydrogen, alkyl (C1-7), halogenoalkyl (C1-4), alkoxy (C1-4)-carbonyl-alkyl (C1-4), cycloalkyl (C3-6), alkenyl (C2-5), alkoxy (C1-4), amino, alkyl (C1-4)-amino or anilino), R2 is hydrogen, alkyl (C1-4), alkoxy (C1-4)-carbonyl-alkyl (C1-4), carboxy-alkyl (C1-4), alkenyl (C2-5) or alkyl (C1-4)-sulfonyl, or R1 and R2 are combined together to form succinyl group, Ring A is phenyl, alkyl (C1-4)-phenyl or halogenophenyl, and n is an integer of 2 to 6, or a pharmaceutically acceptable acid addition salt thereof. The piperazine derivative (I) has an intracranial pressure-lowering activity. Said derivative also has a depressing effect on central nervous system.