3223-55-0

Basic information

• Product Name: 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline
• Synonyms: 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline
• CAS NO: 3223-55-0
• Molecular Weight: 245.283
• Mol File: 3223-55-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline(3223-55-0)
• EPA Substance Registry System: 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline(3223-55-0)

Safety Data

• Hazardous Substances Data: 3223-55-0(Hazardous Substances Data)

Upstream product

• 119-65-3 isoquinoline 
• 59635-52-8 N-(phenylsulfonyl)benzohydrazonoyl chloride 
• 2746-49-8 benzaldehyde isoquinolin-1-ylhydrazone 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 15793-94-9 1-hydrazino-isoquinoline 
• 100-52-7 benzaldehyde 

Relevant articles and documents

I2-TBHP-catalyzed one-pot highly efficient synthesis of 4,3-fused 1,2,4-triazoles from: N -tosylhydrazones and aromatic N-heterocycles via intermolecular formal 1,3-dipolar cycloaddition

I2-TBHP-catalyzed azomethine imine generation and subsequent regioselective 1,3-dipolar cycloaddition (DC) with aromatic N-heterocycles was developed to afford various 4,3-fused 1,2,4-triazoles in excellent yields. The method is operationally simple and highly efficient with broad functional group tolerance.

Palladium-catalyzed coupling of aldehyde-derived hydrazones: Practical synthesis of triazolopyridines and related heterocycles

The palladium-catalyzed intermolecular coupling of aldehyde-derived hydrazones with chloroazines, followed by oxidative cyclization under mild conditions afforded access to a broad variety of bicyclic heterocyclic scaffolds (see scheme) that have potentia