322392-06-3Relevant academic research and scientific papers
Stereocontrolled metalloenamine alkylations: Application to the asymmetric synthesis of 4-alkyl-1,2,3,4-tetrahydroisoquinolines
Vicario, Jose L.,Badia, Dolores,Dominguez, Esther,Carrillo, Luisa
, p. 3779 - 3788 (2007/10/03)
A procedure for the asymmetric synthesis of 4-alkyl-1,2,3,4-tetrahydroisoquinolines is described. The key step in the synthetic route is a stereocontrolled metalloenamine alkylation using (R)-(+)-phenylglycinol methyl ether as the chiral auxiliary. Subseq
