322471-93-2

Upstream product

• 322471-87-4 (R)-N-(1-cyano-6-trimethylsilylhex-4-enyl)-4-phenyloxazolidine 
• 120950-81-4 1-iodo-5-trimethylsilyl-3-pentene 
• 101986-32-7 (-)-N-cyanomethyl-4-phenyl-1,3-oxazolidine 
• 322471-90-9 (2R,5R)-1-((R)-2-Hydroxy-1-phenyl-ethyl)-5-vinyl-piperidine-2-carbonitrile 

Downstream Products

• 322471-95-4 (2R,5S)-5-ethylpipecolic acid 

Relevant academic research and scientific papers

Enantioselective synthesis of 5-substituted pipecolic acids using an intramolecular allylsilane-iminium ion cyclization

The application of the intramolecular allylsilane-iminium ion cyclization reaction for the enantioselective synthesis of piperidine derivatives is described. The synthetic potential of this methodology is demonstrated by the enantioselective synthesis of