322765-92-4

Upstream product

• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 2460-33-5 3,4-dimethoxyphenylpyruvic acid 
• 322765-89-9 3,4-bis-(3,4-dimethoxy-phenyl)-1-[2-(4-methoxy-phenyl)-ethyl]-1H-pyrrole-2,5-dicarboxylic acid 
• 322765-90-2 3,4-bis(3,4-dimethoxyphenyl)-1-(4-methoxyphenethyl)-1H-pyrrole 
• 322765-94-6 2-bromo-2-(3,4-dimethoxyphenyl)acetic acid-2,2,2-trichloroethyl ester 
• 322765-91-3 {3,4-bis-(3,4-dimethoxy-phenyl)-5-[(3,4-dimethoxy-phenyl)-(2,2,2-trichloro-ethoxycarbonyl)-methyl]-1-[2-(4-methoxy-phenyl)-ethyl]-1H-pyrrol-2-yl}-(3,4-dimethoxy-phenyl)-acetic acid 2,2,2-trichloro-ethyl ester 

Relevant academic research and scientific papers

One-pot AgOAc-mediated synthesis of polysubstituted pyrroles from primary amines and aldehydes: Application to the total synthesis of purpurone

A simple and efficient method for the synthesis of 1,3,4-trisubstituted or 3,4-disubstituted pyrroles has been developed. The reaction represents the first time that pyrroles are synthesized directly from readily available aldehydes and amines (anilines)

First total synthesis of the marine alkaloids purpurone and ningalin C

Purpurone is obtained from 3-(3,4-dimethoxyphenyl)pyruvic acid, 2-(4-methoxyphenyl)ethylamine and 2',2',2'-trichloroethyl 2-bromo-2-(3,4-dimethoxyphenyl)acetate in seven steps with an overall yield of 11%. Ningalin C is synthesized from 1-[2-(3,4-dimethox