32292-95-8Relevant academic research and scientific papers
(C6F5)3B Catalyzed Chemoselective and ortho-Selective Substitution of Phenols with α-Aryl α-Diazoesters
Yu, Zhunzhun,Li, Yongfeng,Shi, Jiameng,Ma, Ben,Liu, Lu,Zhang, Junliang
, p. 14807 - 14811 (2016)
The development of an efficient method for the site-selective substitution of unprotected phenols has long been considered as an attractive but challenging task. Herein, we describe a highly chemo- and ortho-selective substitution reaction of phenols with α-aryl α-diazoacetates with commercially available (C6F5)3B as the catalyst. This reaction proceeds under simple and mild conditions with high efficiency, it features a wide substrate scope and can be easily scaled up.
