32298-34-3 Usage
General Description
2-[(2-methoxyphenyl) methyl] butanedioic acid, also known as Methoxyphenyl Acetone or MPA, is an organic compound with a molecular formula C12H14O4. It is a white, crystalline solid commonly used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. MPA is a chiral compound with two enantiomers, each with distinct properties and uses. It is a common reagent in organic chemistry and is used as a building block in the synthesis of various organic compounds. MPA is also known for its use as a precursor to the synthesis of novel drugs and in various chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 32298-34-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,9 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 32298-34:
(7*3)+(6*2)+(5*2)+(4*9)+(3*8)+(2*3)+(1*4)=113
113 % 10 = 3
So 32298-34-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O5/c1-17-10-5-3-2-4-8(10)6-9(12(15)16)7-11(13)14/h2-5,9H,6-7H2,1H3,(H,13,14)(H,15,16)
32298-34-3Relevant articles and documents
Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles
Zhang, Yong-Kang,Plattner, Jacob J.,Freund, Yvonne R.,Easom, Eric E.,Zhou, Yasheen,Ye, Long,Zhou, Huchen,Waterson, David,Gamo, Francisco-Javier,Sanz, Laura M.,Ge, Min,Li, Zhiya,Li, Lingchao,Wang, Hailong,Cui, Han
, p. 1299 - 1307 (2012/03/26)
A series of new boron-containing benzoxaborole compounds was designed and synthesized for a continuing structure-activity relationship (SAR) investigation to assess the antimalarial activity changes derived from side-chain structural variation, substituent modification on the benzene ring and removal of boron from five-membered oxaborole ring. This SAR study demonstrated that boron is required for the antimalarial activity, and discovered that three fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles (9, 14 and 20) have excellent potencies (IC50 0.026-0.209 μM) against Plasmodium falciparum.
