32313-85-2Relevant academic research and scientific papers
Transesterification/Acylation of Secondary Alcohols Mediated by N-Heterocyclic Carbene Catalysts
Singh, Rohit,Kissling, Rebecca M.,Letellier, Marie-Anne,Nolan, Steven P.
, p. 209 - 212 (2004)
N-Heterocyclic carbenes (NHC) are efficient catalysts for transesterification/acylation reactions involving secondary alcohols. The catalytic transformations are carried out employing low catalyst loadings in convenient reaction times at room temperature.
Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens
Hatzakis, Nikos S.,Smonou, Ioulia
, p. 325 - 337 (2007/10/03)
A new asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens has been found. Although alcohols are not the natural substrates for this enzyme, a high R enantioselectivity was observed. Stereochemical studies showed that variations in substrate structure lead to strong variations in enantioselectivity. The highest enantioselectivities are obtained when the β-carbon of the secondary alcohol is tertiary or quaternary.
