32315-92-7Relevant academic research and scientific papers
CYCLIN-DEPENDENT KINASE INHIBITORS
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Page/Page column 208, (2020/07/15)
Described herein are compounds and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, methods of treatment, and medical uses. The compounds described herein are modulators of cyclin-dependent kinases, and are useful in the treatment or alleviation of protein kinase associated disorders, including cancer, infectious diseases, autoimmune diseases, or cardiovascular diseases.
Preparation of ionic liquid-based vilsmier reagent from novel multi-purpose dimethyl formamide-like ionic liquid and its application
Hullio, Ahmed Ali,Mastoi
experimental part, p. 1647 - 1657 (2012/09/21)
In continuation of research to explore the applied potential of DMF-like ionic liquid, the ionic liquid version of N,N-dimethyliminiumchloride (Vilsmier reagent) has been synthesized from DMF-like ionic liquid and tested effectively for its capacity to achieve more useful organic transformations. The results show that DMF-like ionic liquid is world's first task specific ionic liquid which has catalyzed numerous diverse type of reaction and is multipurpose in its application. Thus a new term for this DMF-like ionic liquid has been coined that is DMF-like "multipurpose" ionic liquid. Copyright
First multipurpose task specific ionic liquid: Designing and synthesis of novel dimethyl formamide-like ionic liquid and its applications as a green solvent alternative to dimethyl formamide dependent reactions
Hullio, Ahmed Ali,Mastoi,Khan, Khalid
experimental part, p. 5411 - 5418 (2012/06/29)
A novel imidazole based task specific ionic liquid with dimethyl formamide (DMF) functionality has been designed and synthesized. The proposed dimethyl formamide like task specific can be used as a green alternative solvent-cum-organocatalyst for wide range of organic reactions which essentially depend on DMF. Dimethyl formamide as a solvent, due to its inherited structural features is found to affect the outcome of many reactions. Some of DMF-dependent reactions are investigated in its ionic liquid version with encouraging results. DMFlike ionic liquid acts both as a green reaction media and recyclable organocatalyst. Main advantages include easy reaction procedure, short reaction duration, easy work up and moreover the wide scope applications.
