32317-27-4Relevant academic research and scientific papers
Synthesis of polysubstituted phenanthridines via ligand-free copper-catalyzed annulation
Chen, Yan-Fu,Hsieh, Jen-Chieh
, p. 4642 - 4645 (2014)
A novel procedure for the cascade reaction of the addition of a Grignard reagent to a nitrile with a copper-catalyzed C-N bond coupling was developed, which afforded various polysubstituted phenanthridines in moderate to good yields with tolerance for a wide variety of substrates. Experimental data demonstrated that the reaction proceeded more likely through a Cu(I/III) catalytic cycle.
