323204-67-7Relevant academic research and scientific papers
Convenient route to both enantiomers of chiral 5-hydroxypyrrolidin-2-one and 5-hydroxy-1,5-dihydropyrrol-2-one: Reverse enantioselectivity in lipase-catalyzed kinetic resolution
Takabe,Suzuki,Nishi,Hiyoshi,Takamori,Yoda,Mase
, p. 9859 - 9863 (2000)
High enantioselectivity was achieved in the lipase-catalyzed kinetic resolution of 5-hydroxypyrrolidin-2-one and 5-hydroxy-1,5-dihydropyrrol-2-one derivatives. Lipase PS and Novozym 435 were the successful catalysts (E=>1000). The acetylation of the N-pro
