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4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride, commonly known as Tosyl chloride, is a chemical compound with the molecular formula C7H4ClF3O2S. It is a colorless to pale yellow liquid with a pungent odor and is highly reactive. Tosyl chloride is a versatile raw material used in organic synthesis, particularly in the preparation of sulfonyl chlorides, which serve as important intermediates in the production of pharmaceuticals, agrochemicals, and dyes.

32333-53-2

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32333-53-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity allows for the formation of sulfonyl chlorides, which are essential building blocks in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, Tosyl chloride is utilized as a precursor for the synthesis of sulfonyl chlorides, which are vital in the production of various agrochemicals, including herbicides and insecticides.
Used in Dye Industry:
4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is employed as a raw material in the synthesis of dyes, contributing to the development of a wide range of colorants used in various applications, such as textiles, plastics, and printing inks.
Used in Chemical Analysis:
Tosyl chloride is used as a reagent for the micro analysis of hydroxyl groups, amines, and amino acids. Its reactivity enables the detection and quantification of these functional groups in various chemical and biological samples.
Safety Precautions:
Due to the hazardous nature of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride, it is crucial to take proper precautions when handling 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride. This includes the use of protective equipment, such as gloves, goggles, and lab coats, as well as adhering to safe handling procedures to minimize the risk of exposure and potential harm.

Check Digit Verification of cas no

The CAS Registry Mumber 32333-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,3,3 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 32333-53:
(7*3)+(6*2)+(5*3)+(4*3)+(3*3)+(2*5)+(1*3)=82
82 % 10 = 2
So 32333-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H3Cl2F3O2S/c8-6-2-1-4(15(9,13)14)3-5(6)7(10,11)12/h1-3H

32333-53-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • TCI America

  • (C2705)  4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride  >98.0%(GC)(T)

  • 32333-53-2

  • 1g

  • 370.00CNY

  • Detail
  • TCI America

  • (C2705)  4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride  >98.0%(GC)(T)

  • 32333-53-2

  • 5g

  • 1,290.00CNY

  • Detail
  • Alfa Aesar

  • (H33233)  4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride, 96%   

  • 32333-53-2

  • 1g

  • 4830.0CNY

  • Detail
  • Alfa Aesar

  • (H33233)  4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride, 96%   

  • 32333-53-2

  • 10g

  • 5166.0CNY

  • Detail

32333-53-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride

1.2 Other means of identification

Product number -
Other names 4-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32333-53-2 SDS

32333-53-2Relevant academic research and scientific papers

Cyclic amine derivatives and methods of use

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Page/Page column 42-43, (2010/02/14)

Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

ORGANIC COMPOUNDS

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Page/Page column 82, (2010/02/15)

There are provided according to the invention compounds of formula (I), in free or salt form, wherein R1, R2, R3, R4, R5, R6, Q, W, X, m, n and p are as described in the specification, process for preparing them, and their use as pharmaceuticals.

CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ

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Page 123; 124, (2010/02/09)

Compounds of formula (I) are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation mediated by Bradykinin. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes wherein q, t, R, Ra, Rb, Rc and R2 are as defined herein.

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