323578-38-7

Basic information

• Product Name: N-[6-(hydroxymethyl)-3-pyridinyl]-carbamic acid 1,1-dimethylethyl ester
• Synonyms: N-[6-(hydroxymethyl)-3-pyridinyl]-carbamic acid 1,1-dimethylethyl ester;(6-Hydroxymethyl-pyridin-3-yl)-carbamic acid tert-butyl ester;tert-butyl 6-(hydroxymethyl)pyridin-3-ylcarbamate
• CAS NO: 323578-38-7
• Molecular Formula: C₁₁H₁₆N₂O₃
• Molecular Weight: 224.26
• Mol File: 323578-38-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 139-140 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
• Boiling Point: 317.6±32.0 °C(Predicted)
• Appearance: /
• Density: 1.209±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.73±0.70(Predicted)
• CAS DataBase Reference: N-[6-(hydroxymethyl)-3-pyridinyl]-carbamic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[6-(hydroxymethyl)-3-pyridinyl]-carbamic acid 1,1-dimethylethyl ester(323578-38-7)
• EPA Substance Registry System: N-[6-(hydroxymethyl)-3-pyridinyl]-carbamic acid 1,1-dimethylethyl ester(323578-38-7)

Safety Data

• Hazardous Substances Data: 323578-38-7(Hazardous Substances Data)

Usage

Uses

tert-Butyl 6-(Hydroxymethyl)pyridin-3-ylcarbamate, is a reagent in the monitoring of dynamic glycosylation in vivo using supersensitive click chemistry in mammalian cells and in early zebra fish embryogenesis.

Upstream product

• 3222-47-7 6-methylnicotinic acid 
• 24242-20-4 5-amino-pyridine-2-carboxylic acid 
• 119830-47-6 ethyl 3-amino-pyridine-6-carboxylate 
• 100-26-5 Pyridine-2,5-dicarboxylic acid 
• 17874-76-9 6-(methoxycarbonyl)nicotinic acid 
• 2243961-42-2 methyl 5-(N,N-di-tert-butyloxycarbonyl)amino-2-pyridinecarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 
• 1078129-19-7 ethyl 5-(tert-butoxycarbonylamino)picolinate 
• 131052-40-9 methyl 5-[N-(tert-butoxycarbonyl)amino]-pyridine-2-carboxylate 
• 323578-37-6 tert-butyl N-(6-methylpyridin-3-yl)carbamate 

Downstream Products

• 1203486-73-0 tert-butyl 6-(morpholinomethyl)pyridin-3-ylcarbamate 
• 873651-92-4 (5-aminopyridin-2-yl)methanol 

Relevant articles and documents

INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS

Disclosed herein are compounds of formula (I): and salts thereof. Also disclosed are compositions comprising compounds of formula I and compounds of formula I for use in treating or preventing bacterial infections.

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.