873651-92-4

Basic information

• Product Name: 3-AMINO-6-PYRIDINEMETHANOL
• Synonyms: 3-AMINO-6-PYRIDINEMETHANOL;2-PYRIDINEMETHANOL, 5-AMINO-;3-Amino-6-pyridinemethanol ,97%;(5-aMinopyridin-2-yl)Methanol;5-AMino-2-(hydroxyMethyl)pyridine;(5-Amino-pyridin-2-yl)-methanol dihydrochloride;5-amino-2-pyridinemethanol
• CAS NO: 873651-92-4
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14
• Mol File: 873651-92-4.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 332.7 °C at 760 mmHg
• Flash Point: 155 °C
• Appearance: /
• Density: 1.257 g/cm³
• Vapor Pressure: 5.72E-05mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 13.40±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-6-PYRIDINEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-6-PYRIDINEMETHANOL(873651-92-4)
• EPA Substance Registry System: 3-AMINO-6-PYRIDINEMETHANOL(873651-92-4)

Safety Data

• Hazardous Substances Data: 873651-92-4(Hazardous Substances Data)

Usage

General Description

3-AMINO-6-PYRIDINEMETHANOL is a chemical compound with the molecular formula C6H8N2O. It is a white to off-white solid that is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs and drug substances. It is a derivative of pyridine and contains an amino group and a hydroxyl group, making it a versatile building block for the synthesis of diverse organic compounds. 3-AMINO-6-PYRIDINEMETHANOL is also used in the production of agrochemicals and as a reagent in various chemical processes. It has potential applications in the field of medicinal chemistry, as well as in the development of new materials and catalysts.

InChI:InChI=1/C6H8N2O/c7-5-1-2-6(4-9)8-3-5/h1-3,9H,4,7H2

Upstream product

• 55338-73-3 5-amino-2-cyanopyridine 
• 39658-41-8 ethyl-6-amino-nicotinate 
• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 
• 323578-38-7 tert-butyl N-[6-(hydroxymethyl)pyridin-3-yl]carbamate 
• 17874-76-9 6-(methoxycarbonyl)nicotinic acid 
• 131052-40-9 methyl 5-[N-(tert-butoxycarbonyl)amino]-pyridine-2-carboxylate 
• 100-26-5 Pyridine-2,5-dicarboxylic acid 
• 24242-20-4 5-amino-pyridine-2-carboxylic acid 
• 119830-47-6 ethyl 3-amino-pyridine-6-carboxylate 

Downstream Products

• 1421472-13-0 phenyl 6-(hydroxymethyl)pyridin-3-ylcarbamate 

Relevant articles and documents

Compound serving as protein kinase inhibitor and application of compound

The invention discloses a compound used as a protein kinase inhibitor and application of the compound, the compound has an obvious inhibition effect on protein kinase activity, can be used as a BTK inhibitor for preparing medicines for treating BTK-mediated diseases such as malignant tumors, autoimmune diseases and the like, and has wide application prospect.

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders and primary brain cancer. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders and primary brain cancer.

BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS

Disclosed are compounds of Formula (I) to (VIII): (I) (II) (III) (IV) (V) (VI) (VII) (VIII); or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof, wherein R3 is a bicyclic heteroaryl group substituted with zero to 3 R3a; and R1, R2, R3a, R4, and n are defined herein. Also disclosed are methods of using such compounds as PAR4 inhibitors, and pharmaceutical compositions comprising such compounds. These compounds are useful in inhibiting or preventing platelet aggregation, and are useful for the treatment of a thromboembolic disorder or the primary prophylaxis of a thromboembolic disorder.