3236-55-3

Upstream product

• 623-26-7 terephthalonitrile 
• 421-20-5 Methyl fluorosulfonate 
• 96-31-1 N,N'-Dimethylurea 
• 100-21-0 terephthalic acid 

Downstream Products

• 142739-63-7 N,N'-Dibutyl-N,N'-dimethyl-terephthalamide 
• 177033-62-4 N,N',N,N'''-tetramethyl-p-phenylene-bis-amidine 
• 66661-41-4 N,N'-Bis-(chlormethyl)-terephthalamid 

Relevant academic research and scientific papers

Zirconyl chloride: An efficient, water-tolerant, and reusable catalyst for the synthesis of N-methylamides

ZrOCl28H2O is a highly effective, water-tolerant, and reusable catalyst for the direct condensation of carboxylic acids and N,N-dimethylurea under microwave irradiation to give the corresponding N-methylamides in moderate to excellent yields. Notably, ZrOCl 28H2O is a potentially useful green catalyst due to its low toxicity, easy availability, low cost, ease of handling, easy recovery, good activity, and reusability. Georg Thieme Verlag Stuttgart ? New York.

N-methylation of substituted benzonitriles with methyl fluorosulfonate

Substituted benzonitriles ArCN treated at 20-70°C with methyl fluorosulfonate yield the corresponding N-methylbenzamides ArCONHMe. Compounds with two cyano groups afford N,N′-methylated diamides.